Category: 321-28-8

On August 20, 2021, Zhao, Yue; Yu, Congjun; Liang, Wenjing; Patureau, Frederic W. published an article.Application of 321-28-8 The title of the article was Photochemical (Hetero-)Arylation of Aryl Sulfonium Salts. And the article contained the following:

The construction of (hetero)biaryls, which are ubiquitous scaffolds among medical substances, functional materials, and agrochems., constitutes a key application of cross-coupling methods. However, these usually require multiple synthetic steps. Herein, we report a simple photoinduced and catalyst-free C-H/C-H (hetero)arylation cross-coupling through aryl thianthrenium salts, which are formed site-selectively by direct C-H functionalization. The key to this approach is the UV-light, which can disrupt the C-S bond to form thianthrene radical cations and aryl radicals. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Application of 321-28-8

The Article related to aryl thianthrenium salt heteroarene light photochem arylation, heterobiaryl preparation, Heterocyclic Compounds (One Hetero Atom): Furans and other aspects.Application of 321-28-8

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On February 28, 2013, Magalhaes, Ana L.; Da Silva, Francisco A.; Silva, Carlos M. published an article.Product Details of 321-28-8 The title of the article was Free-volume model for the diffusion coefficients of solutes at infinite dilution in supercritical CO2 and liquid H2O. And the article contained the following:

A new free-volume model for tracer diffusion coefficients in supercritical CO2 and liquid water is proposed in this work. It embodies the concepts of free volume and activation energy. The free volume is calculated by the Carnahan-Starling expression, and the necessary effective hard sphere diameter was taken from a previous publication. The model is explicit, straightforward, contains one parameter per system (activation energy), and only requires temperature, solvent d., solute mol. weight, and the solvent LJ constants The validation of the model was accomplished with a large database, comprehending 289 systems with 5485 data points, and achieved only 3.56% of error. The fine predictive capability of the new expression was also demonstrated. The correlations of Wilke-Chang, Tyn-Calus, He-Yu-Su, Zhu et al., and Dymond were adopted for comparison, but provided much poorer results and/or prediction values. A spreadsheet for the calculation of D12 is given in Supplementary data. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to supercritical carbon dioxide water dilution solute model diffusion coefficient, Phase Equilibriums, Chemical Equilibriums, and Solutions: Phase Equilibriums, Solubility and other aspects.Product Details of 321-28-8

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On March 12, 2014, Lee, Hong Geun; Milner, Phillip J.; Buchwald, Stephen L. published an article.SDS of cas: 321-28-8 The title of the article was Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides. And the article contained the following:

On the basis of mechanism-driven reaction design, a Pd-catalyzed nucleophilic fluorination of aryl bromides and iodides has been developed. The method exhibits a broad substrate scope, especially with respect to nitrogen-containing heteroaryl bromides, and proceeds with minimal formation of the corresponding reduction products. A facilitated ligand modification process was shown to be critical to the success of the reaction. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).SDS of cas: 321-28-8

The Article related to palladium catalyzed nucleophilic fluorination aryl bromide iodide ligand modification, aryl fluoride preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.SDS of cas: 321-28-8

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Ether – Wikipedia,
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Jakobsson, Jimmy Erik; Riss, Patrick Johannes published an article in 2018, the title of the article was Transition metal free, late-stage, regiospecific, aromatic fluorination on a preparative scale using a KF/crypt-222 complex.Safety of 1-Fluoro-2-methoxybenzene And the article contains the following content:

The development of a convenient, regioselective, aromatic fluorination method of hypervalent iodonium ylides for synthesizing fluoro-arenes on a preparative scale was reported. This transition metal free, nucleophilic methodol. provided good yields for sterically hindered substrates, irresp. of activation. The methodol. simplified reference synthesis for PET imaging. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Safety of 1-Fluoro-2-methoxybenzene

The Article related to phenyl iodaneylidene preparation kf crypt 222 regioselective green fluorination, fluorobenzene preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Safety of 1-Fluoro-2-methoxybenzene

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On February 20, 2013, Fier, Patrick S.; Luo, Jingwei; Hartwig, John F. published an article.Category: ethers-buliding-blocks The title of the article was Copper-Mediated Fluorination of Arylboronate Esters. Identification of a Copper(III) Fluoride Complex. And the article contained the following:

A method for the direct conversion of arylboronate esters to aryl fluorides under mild conditions with readily available reagents is reported. Tandem reactions have also been developed for the fluorination of arenes and aryl bromides through arylboronate ester intermediates. Mechanistic studies suggest that this fluorination reaction occurs through facile oxidation of Cu(I) to Cu(III), followed by rate-limiting transmetalation of a bound arylboronate to Cu(III). Fast C-F reductive elimination is proposed to occur from an aryl-copper(III)-fluoride complex. Cu(III) intermediates have been generated independently and identified by NMR spectroscopy and ESI-MS. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Category: ethers-buliding-blocks

The Article related to copper catalyzed fluorination arylboronate ester mechanism, tandem fluorination arene aryl bromide, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Category: ethers-buliding-blocks

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Font, Marc; Spencer, Andrew R. A.; Larrosa, Igor published an article in 2018, the title of the article was meta-C-H arylation of fluoroarenes via traceless directing group relay strategy.Product Details of 321-28-8 And the article contains the following content:

While several methods for the ortho selective arylation of fluoroarenes, meta-functionalization has never been achieved. We report a new methodol., based on the traceless directing group relay concept, leading to the first meta-selective (hetero)arylation of fluoroarenes. In this strategy, CO2 is introduced as a transient directing group, to control a Pd-catalyzed arylation meta to the fluoro functionality, prior to its release in a sequential, one-pot fashion. This method has shown compatibility with a number of functional groups and substitution patterns in both the fluoroarene core and aryl iodide coupling partners, and proceeds with complete meta-selectivity and mono vs. bis-arylation selectivity. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Product Details of 321-28-8

The Article related to fluoro biaryl preparation regioselective, aryl fluoride aryl iodide arylation decarboxylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Product Details of 321-28-8

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On February 6, 2015, Fujimoto, Teppei; Ritter, Tobias published an article.Name: 1-Fluoro-2-methoxybenzene The title of the article was PhenoFluorMix: Practical Chemoselective Deoxyfluorination of Phenols. And the article contained the following:

A practical deoxyfluorination with novel deoxyfluorinating reagent PhenoFluorMix, a mixture of N,N’-1,3-bis(2,6-diisopropylphenyl)chloroimidazolium chloride and CsF, is presented. PhenoFluorMix overcomes the challenges associated with hydrolysis of PhenoFluor. PhenoFluorMix does not hydrolyze, is readily available on decagram scale, and is storable in air. In this paper, we demonstrate the practicality of the reagent and exhibit the deoxyfluorination of a variety of phenols and heterocycles. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Name: 1-Fluoro-2-methoxybenzene

The Article related to aryl halide chemoselective synthesis, phenol heterocycle deoxyfluorination phenofluormix, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Name: 1-Fluoro-2-methoxybenzene

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On October 7, 2020, Pistritto, Vincent A.; Schutzbach-Horton, Megan E.; Nicewicz, David A. published an article.Category: ethers-buliding-blocks The title of the article was Nucleophilic Aromatic Substitution of Unactivated Fluoroarenes Enabled by Organic Photoredox Catalysis. And the article contained the following:

Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Category: ethers-buliding-blocks

The Article related to nucleophilic aromatic substitution unactivated fluoroarene organic photoredox catalysis, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Category: ethers-buliding-blocks

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Ether – Wikipedia,
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On March 31, 2015, Dubbaka, Srinivas Reddy; Gadde, Satyanarayana; Narreddula, Venkateswara Reddy published an article.SDS of cas: 321-28-8 The title of the article was Synthesis of Aryl Fluorides from Potassium Aryltrifluoroborates and Selectfluor Mediated by Iron(III) Chloride. And the article contained the following:

The synthesis of fluorinated arenes by the iron-mediated fluorination of potassium aryltrifluoroborates with Selectfluor and potassium fluoride is described. The fluorination reaction uses com. available reagents and without requiring the addition of exogenous ligands. Fluorinated compounds were obtained in moderate to good yields under mild reaction conditions. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).SDS of cas: 321-28-8

The Article related to aryl fluoride preparation aryltrifluoroborate fluorination selectfluor iron trichloride, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.SDS of cas: 321-28-8

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On October 4, 2013, Ichiishi, Naoko; Canty, Allan J.; Yates, Brian F.; Sanford, Melanie S. published an article.Computed Properties of 321-28-8 The title of the article was Cu-Catalyzed Fluorination of Diaryliodonium Salts with KF. And the article contained the following:

A mild Cu-catalyzed nucleophilic fluorination of unsym. diaryliodonium salts with KF is described. This protocol preferentially fluorinates the smaller aromatic ligand on iodine(III). The reaction exhibits a broad substrate scope and proceeds with high chemoselectivity and functional group tolerance. E.g., in presence of Cu(OTf)2 and 18-crown-6, nucleophilic fluorination of diaryliodonium salt (I) with KF gave 85% II and mesityl fluoride (99:1). DFT calculations implicate a CuI/CuIII catalytic cycle. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Computed Properties of 321-28-8

The Article related to copper catalyst nucleophilic fluorination diaryliodonium salt potassium fluoride, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Computed Properties of 321-28-8

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Ether – Wikipedia,
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