Needham, Russell J. et al. published their research in Journal of Inorganic Biochemistry in 2020 | CAS: 111-77-3

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Synthetic Route of C5H12O3

Structure-activity relationships for osmium(II) arene phenylazopyridine anticancer complexes functionalized with alkoxy and glycolic substituents was written by Needham, Russell J.;Bridgewater, Hannah E.;Romero-Canelon, Isolda;Habtemariam, Abraha;Clarkson, Guy J.;Sadler, Peter J.. And the article was included in Journal of Inorganic Biochemistry in 2020.Synthetic Route of C5H12O3 This article mentions the following:

Twenty-four novel organometallic osmium(II) phenylazopyridine (AZPY) complexes have been synthesized and characterized; [Os(η6-arene)(5-RO-AZPY)X]Y, where arene = p-cym or bip, AZPY is functionalized with an alkoxyl (O-R, R = Me, Et, nPr, iPr, nBu) or glycolic (O-{CH2CH2O}nR*, n = 1-4, R* = H, Me, or Et) substituent on the pyridyl ring para to the azo-bond, X is a monodentate halido ligand (Cl, Br or I), and Y is a counter-anion (PF–6, CF3SO–3 or IO–3). X-ray crystal structures of two complexes confirmed their ‘half-sandwich’ structures. Aqueous solubility depended on X, the AZPY substituents, arene, and Y. Iodido complexes are highly stable in water (X = I >>> Br > Cl), and exhibit the highest antiproliferative activity against A2780 (ovarian), MCF-7 (breast), SUNE1 (nasopharyngeal), and OE19 (oesophageal) cancer cells, some attaining nanomolar potency and good cancer-cell selectivity. Their activity and distinctive mechanism of action is discussed in relation to hydrophobicity (RP-HPLC capacity factor and Log Po/w), cellular accumulation, electrochem. reduction (activation of azo bond), cell cycle anal., apoptosis and induction of reactive oxygen species (ROS). Two complexes show ca. 4x higher activity than cisplatin in the National Cancer Institute (NCI) 60-cell line five-dose screen. The COMPARE algorithm of their datasets reveals a strong correlation with one another, as well as anticancer agents olivomycin, phyllanthoside, bouvardin and gamitrinib, but only a weak correlation with cisplatin, indicative of a different mechanism of action. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Synthetic Route of C5H12O3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.Synthetic Route of C5H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Nematollahi, Davood et al. published their research in International Journal of Electrochemical Science in 2009 | CAS: 66943-05-3

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane

Electrochemical oxidation of catechol in the presence of some azacrown ethers and transition metal ions in acetonitrile was written by Nematollahi, Davood;Mohammadi-Behzad, Leila. And the article was included in International Journal of Electrochemical Science in 2009.Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane This article mentions the following:

The electrochem. oxidation of catechol (H2Q) has been studied in the absence and presence of 1,10.diaza-18-crown-6 (DA18C6), 1,7-diaza-15-crown-5 (DA15C5) and aza-15-crown-5 (A15C5) and also, in the presence of some transition metal ions (Zn2+, Ni2+ and Cd2+) in acetonitrile containing tetra-n-butylammonium perchlorate as supporting electrolyte, by means of cyclic voltammetry. The results indicate an ECCE(E)C mechanism in electrochem. oxidation of catechol (H2Q) in the presence of azacrown ethers a-c. The cyclic voltammetric data were analyzed by digital simulation to confirm and to measure the homogeneous parameters for the suggested electrode mechanism. The calculated observed homogeneous rate constants (kobs) for the reaction of electrochem. generated cation radical (H2Q+) with azacrown ethers 2a-c was found to vary in the order DA18C6 >DA15C5 >A15C5. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Quality Control of 1,4,7,10-Tetraoxa-13-azacyclopentadecane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Ikeda, Taichi et al. published their research in Bulletin of the Chemical Society of Japan in 2020 | CAS: 60221-37-6

2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C11H22O5

Tetra-Branched Tetra-Cationic Ionic Liquids: Effects of Spacer and Tail Structure on Physical Properties was written by Ikeda, Taichi. And the article was included in Bulletin of the Chemical Society of Japan in 2020.Synthetic Route of C11H22O5 This article mentions the following:

Herein, the synthesis of ten tetra-branched tetra-cationic ionic liquids, which consist of a pentaerythritol-based core, alkylene or ethylenedioxy spacers, imidazolium cationic units, and short alkyl tails, is described. The phys. properties of the tetra-cations, including their glass transition and thermal decomposition temperatures, densities, viscosities, and ionic conductivities, were investigated. The tetra-cations were analyzed to determine the effects of the spacer and tail structure on the above-mentioned phys. properties. The spacer unit located between the pentaerythrityl core and cationic unit was confirmed to be the key for improving ionic conductivity A maximum ionic conductivity of 2.8 x 10-4 S cm-1 (25°C under anhydrous conditions) and a min. viscosity of 1.6 Pa s (25°C) were observed While the phys. values of the tetra-cationic ionic liquids are close to those of di-cationic ionic liquids, their structure-property relationship is similar to that of poly-cations rather than di-cations. In the experiment, the researchers used many compounds, for example, 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6Synthetic Route of C11H22O5).

2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C11H22O5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Alexander, Varughese M. et al. published their research in Synlett in 2003 | CAS: 75581-11-2

4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Related Products of 75581-11-2

Solvent-free iodination of arenes at room temperature was written by Alexander, Varughese M.;Khandekar, Amit C.;Samant, Shriniwas D.. And the article was included in Synlett in 2003.Related Products of 75581-11-2 This article mentions the following:

Silica supported bismuth(III)nitrate pentahydrate (BNP-SiO2) was prepared under simple co-grinding condition. The iodination of aromatic compounds using BNP-SiO2 and mol. iodine under solvent-free conditions is described. The reaction occurred in the solid state at room temperature, yielding the corresponding mono-iodo derivative in good yields. However, less activated aromatics required longer reaction time with comparatively less yield. In the experiment, the researchers used many compounds, for example, 4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2Related Products of 75581-11-2).

4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Related Products of 75581-11-2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Heasley, Brian H. et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2004 | CAS: 63071-12-5

(6-Methoxypyridin-2-yl)methanol (cas: 63071-12-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Product Details of 63071-12-5

A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist was written by Heasley, Brian H.;Jarosz, Renata;Carter, Karen M.;Jenny Van, S.;Lynch, Kevin R.;Macdonald, Timothy L.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2004.Product Details of 63071-12-5 This article mentions the following:

A recently reported dual LPA1/LPA3 receptor antagonist (1) has been modified to modulate the basicity, sterics, and dipole moment of the 2-pyridyl moiety. Addnl., the implications of installing nonhydrolyzable phosphate head group isosteres with regard to antagonist potency and selectivity at LPA receptors is described. This study has resulted in the development of the first nonhydrolyzable and presumably phosphatase-resistant LPA3-selective antagonist reported to date. In the experiment, the researchers used many compounds, for example, (6-Methoxypyridin-2-yl)methanol (cas: 63071-12-5Product Details of 63071-12-5).

(6-Methoxypyridin-2-yl)methanol (cas: 63071-12-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Product Details of 63071-12-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gao, Jinliang et al. published their research in Jingxi Huagong in 2007 | CAS: 1132-95-2

1,1-Diisopropoxycyclohexane (cas: 1132-95-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Application In Synthesis of 1,1-Diisopropoxycyclohexane

A convenient method for synthesis of 1,1-diisopropoxycyclohexane was written by Gao, Jinliang;Li, Xianggao;Hu, Cong;Wang, Shirong;Feng, Yaqing. And the article was included in Jingxi Huagong in 2007.Application In Synthesis of 1,1-Diisopropoxycyclohexane This article mentions the following:

A method for the synthesis of the title compound [i.e., cyclohexanone diisopropyl ketal, 1,1-bis(1-methylethoxy)cyclohexane] is reported here. A one-pot reaction of cyclohexanone with tri-Me orthoformate using p-toluenesulfonic acid as catalyst in isopropanol provided 1,1-dimethoxycyclohexane. This compound (without separation) reacted further with isopropanol to form the title compound by distilling off the low-boiling product. Structure of the title compound was characterized by elementary anal., 1HNMR and IR. The optimized process conditions and results were n(cyclohexanone) : n(tri-Me orthoformate) : n(isopropanol) : n(p-toluenesulfonic acid) = 1:1.1:4:0.007, number of theor. plates 5, reaction time 15 h, yield 61.5% and GC content 96.4% (area normalization method). In the experiment, the researchers used many compounds, for example, 1,1-Diisopropoxycyclohexane (cas: 1132-95-2Application In Synthesis of 1,1-Diisopropoxycyclohexane).

1,1-Diisopropoxycyclohexane (cas: 1132-95-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Application In Synthesis of 1,1-Diisopropoxycyclohexane

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Geysens, Pieter et al. published their research in RSC Advances in 2020 | CAS: 112-49-2

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Computed Properties of C8H18O4

Reversible electrodeposition and stripping of magnesium from solvate ionic liquid-tetrabutylammonium chloride mixtures was written by Geysens, Pieter;Fransaer, Jan;Binnemans, Koen. And the article was included in RSC Advances in 2020.Computed Properties of C8H18O4 This article mentions the following:

The physicochem. properties of three new magnesium-containing solvate ionic liquids are reported. The solvation structures were analyzed by Raman spectroscopy, revealing a solvent separated ion pair structure at room temperature The reversible electrodeposition and stripping of magnesium from mixtures of these solvate ionic liquids and tetra-n-butylammonium chloride is described. The electrolytes are significantly less volatile than similar dilute electrolytes, even at elevated temperatures and the deposition current densities exceed 1 A dm-2 at 80°C. The influence of the chloride concentration on magnesium deposition was studied with cyclic voltammetry and chronopotentiometry. It was found that the stripping of magnesium is governed by two competing reactions, and the addition of tetrabutylammonium chloride to the solvate ionic liquids was necessary to prevent passivation and efficiently strip the deposited magnesium. In the experiment, the researchers used many compounds, for example, 2,5,8,11-Tetraoxadodecane (cas: 112-49-2Computed Properties of C8H18O4).

2,5,8,11-Tetraoxadodecane (cas: 112-49-2) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Computed Properties of C8H18O4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

von Wantoch Rekowski, Margarete et al. published their research in Journal of Medicinal Chemistry in 2013 | CAS: 156635-90-4

(4-((4-Methoxybenzyl)oxy)phenyl)boronic acid (cas: 156635-90-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Recommanded Product: 156635-90-4

Insights into Soluble Guanylyl Cyclase Activation Derived from Improved Heme-Mimetics was written by von Wantoch Rekowski, Margarete;Kumar, Vijay;Zhou, Zongmin;Moschner, Johann;Marazioti, Antonia;Bantzi, Marina;Spyroulias, Georgios A.;van den Akker, Focco;Giannis, Athanassios;Papapetropoulos, Andreas. And the article was included in Journal of Medicinal Chemistry in 2013.Recommanded Product: 156635-90-4 This article mentions the following:

Recently, the structure of BAY 58-2667 bound to the Nostoc sp. H-NOX domain was published. On the basis of this structural information, we designed BAY 58-2667 derivatives and tested their effects on soluble guanylyl cyclase (sGC) activity. Derivative 20 activated sGC 4.8-fold more than BAY 58-2667. Co-crystallization of 20 with the Ns H-NOX domain revealed that the increased conformational distortion at the C-terminal region of αF helix containing 110-114 residues contributes to the higher activation triggered by 20. In the experiment, the researchers used many compounds, for example, (4-((4-Methoxybenzyl)oxy)phenyl)boronic acid (cas: 156635-90-4Recommanded Product: 156635-90-4).

(4-((4-Methoxybenzyl)oxy)phenyl)boronic acid (cas: 156635-90-4) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Recommanded Product: 156635-90-4

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

Gillsch, Franziska et al. published their research in Journal of Organic Chemistry in 2022 | CAS: 105-13-5

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Product Details of 105-13-5

Synthesis and Bioactivity of Ophiofuranones A and B was written by Gillsch, Franziska;Zeng, Haoxuan;Baer, Sofia I.;Schrey, Hedda;Schobert, Rainer. And the article was included in Journal of Organic Chemistry in 2022.Product Details of 105-13-5 This article mentions the following:

Ophiofuranones A (E isomer shown in graphic) and B (Z isomer), metabolites of the fungus Ophiosphaerella korrae, were synthesized in 16 steps and 12%/22% yield. The stereogenic centers were established by Sharpless dihydroxylations and epoxidation, the 1,3-dienes via Wittig or HWE olefinations. The rings were closed through Knoevenagel-type condensation and lactonization. The ophiofuranones proved nontoxic at relevant concentrations against tumor cells, fibroblasts, and various bacteria and fungi. Ophiofuranone A and the monocyclic precursors were weakly active against microbial biofilms. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Product Details of 105-13-5).

(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Product Details of 105-13-5

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem

He, Zhi-yong et al. published their research in Jiangsu Huagong in 2005 | CAS: 5367-32-8

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Category: ethers-buliding-blocks

Synthesis of 5-methoxyindole was written by He, Zhi-yong;Fan, Bi-you. And the article was included in Jiangsu Huagong in 2005.Category: ethers-buliding-blocks This article mentions the following:

Four kinds of synthetic methods of 5-methoxyindole (FMI) are discussed and compared with each other. The 5-bromoindole (FBI) route is economical and effective. The optimum material compounding ratio is obtained by experiment: m(FBI):m(CatB):m(CH3ONa):m(DMF) = 1:0.83:9.75:8.7, FMI is gained by method of direct distillation in later disposal, the yield of product can be reached 78.8% with purity of 99.96%. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Category: ethers-buliding-blocks).

3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Category: ethers-buliding-blocks

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem