Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2398-37-0, name is 1-Bromo-3-methoxybenzene, A new synthetic method of this compound is introduced below., Recommanded Product: 2398-37-0
General procedure: Compound 6a was prepared by reacting 3-bromo-2-methyl-5-thienylboronic acid [50] (4.2 g, 19.0 mmol) with 1-bromo-2-methoxybenzene (3.91 g, 20.9 mmol) in the presence of Pd(PPh3)4 (0.73 g, 0.63 mmol) and Na2CO3 (2 mol L-1, 10 mL) in tetrahydrofuran (THF) (80 mL) for 18 h at 343 K. The reaction was allowed to cool to room temperature. After being extracted with ether, the organic layer was dried over MgSO4, filtered, and concentrated. The crude product was purified by column chromatography on silica gel using petroleum ether as eluent to afford 3.87 g of 6a visible as a buff solid with a 72% yield.
The synthetic route of 2398-37-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Zheng, Chunhong; Pu, Shouzhi; Pang, Zhiyi; Chen, Bing; Liu, Gang; Dai, Yanfeng; Dyes and Pigments; vol. 98; 3; (2013); p. 565 – 574;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem