Recently I am researching about MEDIATED OXIDATIVE TRIFLUOROMETHYLATION; ALPHA-FLUORINATED ETHERS; ALKENES; ARENES; AMINOTRIFLUOROMETHOXYLATION; FUNCTIONALIZATION; THIOETHERS; CHEMISTRY; BONDS, Saw an article supported by the National Key Research and Development Program of China [2016YFA0602900]; NFSCNational Natural Science Foundation of China (NSFC) [21672110, 21925105]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Deng, ZJ; Zhao, MX; Wang, F; Tang, PP. The CAS is 101-84-8. Through research, I have a further understanding and discovery of Diphenyl oxide. HPLC of Formula: C12H10O
Methods for direct C-H trifluoromethoxylation of arenes and heteroarenes are rare, despite the importance of trifluoromethoxylated compounds for pharmaceuticals, agrochemicals, and material sciences. Especially selective C-H trifluoromethoxylation of pyridines remains a formidable challenge. Here we show a general late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagent with trifluoromethoxide anion. The reaction is mediated by silver salts under mild reaction conditions, exhibiting broad substrate scope and wide functional-group compatibility. In addition, ortho-position selective C-H trifluoromethoxylation of pyridines is observed. The method is not only applicable to the gram-scale synthesis of trifluoromethoxylated products but also allows efficient late-stage C-H trifluoromethoxylation of marketed small-molecule drugs, common pharmacophores and natural products. Selective C-H trifluoromethoxylation of pyridines remains a formidable synthetic challenge. Here, the authors report a silver-mediated late-stage C-H trifluoromethoxylation of arenes and heteroarenes as limiting reagents with trifluoromethoxide anion.
HPLC of Formula: C12H10O. About Diphenyl oxide, If you have any questions, you can contact Deng, ZJ; Zhao, MX; Wang, F; Tang, PP or concate me.
Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem