Mills, LR; Graham, JM; Patel, P; Rousseaux, SAL in [Mills, L. Reginald; Graham, Joshua M.; Patel, Purvish; Rousseaux, Sophie A. L.] Univ Toronto, Dept Chem, Davenport Res Labs, 80 St George St, St George, ON M5S 3H6, Canada published Ni-Catalyzed Reductive Cyanation of Aryl Halides and Phenol Derivatives via Transnitrilation in 2019, Cited 49. Recommanded Product: 101-84-8. The Name is Diphenyl oxide. Through research, I have a further understanding and discovery of 101-84-8.
Herein, we report a Ni-catalyzed reductive coupling for the synthesis of benzonitriles from aryl (pseudo)halides and an electrophilic cyanating reagent, 2-methyl-2-phenyl malononitrile (MPMN). MPMN is a bench-stable, carbon-bound electrophilic CN reagent that does not release cyanide under the reaction conditions. A variety of medicinally relevant benzonitriles can be made in good yields. Addition of NaBr to the reaction mixture allows for the use of more challenging aryl electrophiles such as aryl chlorides, tosylates, and triflates. Mechanistic investigations suggest that NaBr plays a role in facilitating oxidative addition with these substrates.
Welcome to talk about 101-84-8, If you have any questions, you can contact Mills, LR; Graham, JM; Patel, P; Rousseaux, SAL or send Email.. Recommanded Product: 101-84-8
Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem