Quality Control of Benzyl ether. Recently I am researching about C-H AMINATION; ACYL HYDRAZIDES; DIETHYL-ETHER; METAL-FREE; HYDROACYLATION; ALDEHYDES; ARENES; GREEN; AUTOXIDATION; CHALLENGES, Saw an article supported by the UCL Graduate School. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Shamsabadi, A; Maruani, A; Ahmed, N; Chudasama, V. The CAS is 103-50-4. Through research, I have a further understanding and discovery of Benzyl ether
Significant advancements in C-N bond formationviaC-H bond functionalisation have made it a staple in the production of nitrogen-containing compounds in both industry and academia. However, transition metal-free synthesis, particularly in the case of C(sp(3))-N formation, has remained a significant challenge to the synthetic community. Herein we report a procedure for alpha-C(sp(3))-H amination of ethereal compounds through use of azodicarboxylates as the nitrogen source and freely-available atmospheric oxygen to access ethereal radical intermediatesviaaerobic C-H activation. The use of fluorinated alcohols as solvent is observed to greatly increase the efficiency of the reaction and we show experimentally and theoretically the key role of H-bonding between fluorinated alcohols and azodicarboxylates. Calculations of the condensed Fukui functions of a H-bonded fluorinated alcohol-azodicarboxylate complex correlates with a significantly increased susceptibility of azodicarboxylates to undergo reaction with radicals, which informs a number of recent reports in the literature.
Quality Control of Benzyl ether. About Benzyl ether, If you have any questions, you can contact Shamsabadi, A; Maruani, A; Ahmed, N; Chudasama, V or concate me.
Reference:
Ether – Wikipedia,
,Ether | (C2H5)2O – PubChem