On April 19, 2019, Huber, Florian; Roesslein, Joel; Gademann, Karl published an article.HPLC of Formula: 321-28-8 The title of the article was Preparation of Indolenines via Nucleophilic Aromatic Substitution. And the article contained the following:
An unusual aromatic substitution to access indolenines is described. 2-(2-Methoxyphenyl)acetonitrile derivatives are reacted with various alkyl and aryl Li reagents to furnish the corresponding indolenine products, constituents of natural products, and cyanine dyes such as indocyanine green. This new method was used to synthesize 41 indolenines with large functional group tolerance, and selected examples were further converted to the corresponding indolenine dyes. Key experiments provide insight into the mechanism of this nucleophilic aromatic substitution. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).HPLC of Formula: 321-28-8
The Article related to indolenine preparation nucleophilic aromatic substitution methoxyphenyl acetonitrile organolithium, aromatic substitution methoxyphenyl acetonitrile organolithium indolenine cyclization and other aspects.HPLC of Formula: 321-28-8
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem