Kaga, Atsushi; Hayashi, Hirohito; Hakamata, Hiroyuki; Oi, Miku; Uchiyama, Masanobu; Takita, Ryo; Chiba, Shunsuke published an article in 2017, the title of the article was Nucleophilic Amination of Methoxy Arenes Promoted by a Sodium Hydride/Iodide Composite.Formula: C7H7FO And the article contains the following content:
A method for the nucleophilic amination of methoxy arenes was established by using sodium hydride (NaH) in the presence of lithium iodide (LiI). This method offers an efficient route to benzannulated nitrogen heterocycles. Mechanistic studies showed that the reaction proceeds through an unusual concerted nucleophilic aromatic substitution. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Formula: C7H7FO
The Article related to benzannulated nitrogen heterocycle preparation, methoxy arene amine nucleophilic amination, dft calculations, amination, nitrogen heterocycles, nucleophilic aromatic substitution, sodium hydride and other aspects.Formula: C7H7FO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem