On May 1, 2020, Van Velthoven, Niels; Henrion, Mickael; Dallenes, Jesse; Krajnc, Andraz; Bugaev, Aram L.; Liu, Pei; Bals, Sara; Soldatov, Alexander V.; Mali, Gregor; De Vos, Dirk E. published an article.Safety of 1,2-Dimethoxybenzene The title of the article was S,O-Functionalized Metal-Organic Frameworks as Heterogeneous Single-Site Catalysts for the Oxidative Alkenylation of Arenes via C-H activation. And the article contained the following:
Heterogeneous single-site catalysts can combine the precise active site design of organometallic complexes with the efficient recovery of solid catalysts. Based on recent progress on homogeneous thioether ligands for Pd-catalyzed C-H activation reactions, a scalable metal-organic framework-based heterogeneous single-site catalyst containing S,O-moieties that increase the catalytic activity of Pd(II) for the oxidative alkenylation of arenes has been developed. The structure of the Pd@MOF-808-L1 catalyst was characterized in detail via solid-state NMR spectroscopy, N2 physisorption, and high-angle annular dark field scanning transmission electron microscopy, and the structure of the isolated palladium active sites could be identified by X-ray absorption spectroscopy. A turnover frequency (TOF) of 8.4 h-1 was reached after 1 h of reaction time, which was 3 times higher than the TOF of standard Pd(OAc)2, ranking Pd@MOF-808-L1 among the most active heterogeneous catalysts ever reported for the nondirected oxidative alkenylation of arenes. Finally, the single-site catalyst promotes the oxidative alkenylation of a broad range of electron-rich arenes, and the applicability of this heterogeneous system was demonstrated by the gram-scale synthesis of industrially relevant products has been reported. The experimental process involved the reaction of 1,2-Dimethoxybenzene(cas: 91-16-7).Safety of 1,2-Dimethoxybenzene
The Article related to arene oxidative alkenylation metal organic framework catalyst regioselective stereoselective, General Organic Chemistry: Synthetic Methods and other aspects.Safety of 1,2-Dimethoxybenzene
Referemce:
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Ether | (C2H5)2O – PubChem