Makkad, Sarabjot Kaur published the artcileπ-Conjugated Chromophore Incorporated Polystyrene Nanobeads as Single Optical Agent for Three-Channel Fluorescent Probe in Bioimaging Application, Synthetic Route of 146370-51-6, the publication is ACS Biomaterials Science & Engineering (2017), 3(8), 1788-1798, database is CAplus and MEDLINE.
Fluorescent polystyrene (PS) nanobeads in the size range ∼70-120 nm incorporating perylene bisimide (PBI-PS) and/or oligo(p-phenylenevinylene) (OPV-PS) were developed by the miniemulsion polymerization technique. A dye loading content (DLC) of <3% was sufficient to impart high fluorescence emission capability to the PS beads. OPV-PS exhibited emission in the range 400-550 nm with peak emission at 450 nm (λex = 350 nm; φFL = 26%); PBI-PS showed emission from 520-650 nm with peak emission at 545 nm (λex = 490 nm; φFL = 9.7%) in 1× PBS buffer, whereas OPV(PBI)-PS nanobeads incorporating both the fluorophores exhibited multicolor emission capabilities (λex from 350 to 490 nm). The nanoparticles were characterized by field-emission SEM (FESEM), TEM and dynamic light scattering (DLS) for size and zeta potential for surface charge. For bioimaging applications, the PS nanoparticles were incubated with HeLa cells. Cell viability anal. involving HeLa cells showed >90% cell viability confirming the biocompatibility of the PS beads. The cellular uptake of the nanoparticles was confirmed by flow cytometry anal. and confocal laser scanning microscopy (CLSM) images. The subcellular localization of the nanoparticles in the cytoplasm could be precisely established by their simultaneous multicolor emission. The PS-based single optical agent presented here that can function as three-channel fluorescent probe to meet the requirements for multicolor bioimaging is advantageous.
ACS Biomaterials Science & Engineering published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, Synthetic Route of 146370-51-6.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem