Burkholder, Timothy P.’s team published research in Bioorganic & Medicinal Chemistry Letters in 25 | CAS: 2944-47-0

Bioorganic & Medicinal Chemistry Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Burkholder, Timothy P. published the artcileDesign and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists, Product Details of C10H14O, the publication is Bioorganic & Medicinal Chemistry Letters (2015), 25(7), 1377-1380, database is CAplus and MEDLINE.

The design, synthesis, and structure activity relationships for a series of indoles, e.g., I, as potent, selective, thyroid hormone receptor β (TRβ) agonists is described. Compounds with >50× binding selectivity for TRβ over TRα were generated and evaluation of compound I from this series in a model of dyslipidemia demonstrated pos. effects on plasma lipid endpoints in vivo.

Bioorganic & Medicinal Chemistry Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem