Madhiri, Nicholas’s team published research in Physical Chemistry Chemical Physics in 5 | CAS: 14807-75-1

Physical Chemistry Chemical Physics published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Safety of Formamidine disulfide dihydrochloride.

Madhiri, Nicholas published the artcileOxyhalogen-sulfur chemistry: kinetics and mechanism of oxidation of formamidine disulfide by acidic bromate, Safety of Formamidine disulfide dihydrochloride, the publication is Physical Chemistry Chemical Physics (2003), 5(19), 4149-4156, database is CAplus.

The kinetics and mechanism of the oxidation of formamidine disulfide, FDS, a dimer and major metabolite of thiourea, by bromate were studied in acidic media. In excess bromate conditions the reaction displays an induction period before formation of Br. The stoichiometry of the reaction is: 7BrO3– + 3[H2N(HN:)CS-]2 + 9H2O → 6NH2CONH2 + 6SO42- + 7Br– + 12H+ (A). In excess oxidant conditions, however, the bromide formed in reaction A reacts with bromate to give Br and a final stoichiometry of: 14BrO3– + 5[H2N(HN:)CS-]2 + 8H2O → 10NH2CONH2 + 10SO42- + 7Br2 + 6H+ (B). The direct reaction of Br and FDS was also studied and its stoichiometry is: 7Br2 + [H2N(HN:)CS-]2 + 10H2O → 2NH2CONH2 + 2SO42- + 14Br– + 18H+ (C). The overall rate of reaction A, as measured by the rate of consumption of FDS, is second order in acid concentrations, indicating the dominance of oxyhalogen kinetics which control the formation of the reactive species HBrO2 and HOBr. The reaction proceeds through an initial cleavage of the S-S bond to give the unstable sulfenic acids which are then rapidly oxidized through the sulfinic and sulfonic acids to give sulfate. The formation of Br coincides with formation of sulfate because the cleavage of the C-S bond to give sulfate occurs at the sulfonic acid stage only. The mechanism derived is the same as that derived for the bromate-thiourea reaction, suggesting that FDS is an intermediate in the oxidation of thiourea to its oxo-acids as well as to sulfate.

Physical Chemistry Chemical Physics published new progress about 14807-75-1. 14807-75-1 belongs to ethers-buliding-blocks, auxiliary class Salt,Thiourea,Amine,Aliphatic hydrocarbon chain, name is Formamidine disulfide dihydrochloride, and the molecular formula is C2H8Cl2N4S2, Safety of Formamidine disulfide dihydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem