Ramachandran, Rangasamy published the artcileEfficient and versatile catalysis of N-alkylation of heterocyclic amines with alcohols and one-pot synthesis of 2-aryl substituted benzazoles with newly designed ruthenium(II) complexes of PNS thiosemicarbazones, Recommanded Product: N-(4-Methoxybenzyl)pyridin-2-amine, the publication is Dalton Transactions (2014), 43(21), 7889-7902, database is CAplus and MEDLINE.
Ru(II) carbonyl complexes with phosphine-functionalized PNS type thiosemicarbazone ligands [RuCl(CO)(EPh3)(L)] (1–6) (E = P or As, L = 2-(2-(diphenylphosphino)benzylidene) thiosemicarbazone (PNS-H), 2-(2-(diphenylphosphino)benzylidene)-N-methylthiosemicarbazone (PNS-Me), 2-(2-(diphenylphosphino)benzylidene)-N-phenylthiosemicarbazone (PNS-Ph)) were synthesized and characterized by elemental anal. and spectroscopy (IR, UV-visible, 1H, 13C, 31P-NMR) as well as ESI mass spectrometry. The mol. structures of complexes 1, 2 and 6 were identified by single-crystal x-ray diffraction anal. The anal. revealed that all the complexes possess a distorted octahedral geometry with the ligand coordinating in a uni-neg. tridentate PNS fashion. All the Ru complexes (1–6) were tested as catalyst for N-alkylation of heteroaromatic amines with alcs. Notably, complex 2 is a very efficient and versatile catalyst towards N-alkylation of a wide range of heterocyclic amines with alcs. Complex 2 can also catalyze the direct amination of 2-nitropyridine with benzyl alc. to the corresponding secondary amine. Also, a preliminary examination of performance for N,N-dialkylation of diamine showed promising results, giving good conversion and high selectivity. N-alkylation of ortho-substituted anilines (-NH2, -OH and -SH) led to the 1-pot synthesis of 2-aryl substituted benzimidazoles, benzoxazoles and benzothiazoles, also revealing the catalytic activity of complex 2.
Dalton Transactions published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Recommanded Product: N-(4-Methoxybenzyl)pyridin-2-amine.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem