Substituent effects on the activation parameters of the reaction between 1,4-benzoquinones and hydrogen peroxide: A combined experimental and theoretical study was written by Jozsa, Eva;Jenei, Laura Barbara;Kegl, Tamas;Osz, Katalin. And the article was included in Journal of Molecular Structure in 2022.Synthetic Route of C9H10O4 This article mentions the following:
Exptl. and theor. results on the aqueous reactions of various substituted 1,4-bnzoquinone derivatives (2-tert-butyl-, 2-methyl-, 2-chloro-, 2,6-dichloro- and the unsubstituted 1,4-benzoquinone) are reported. The rate law of the process was confirmed to be first order with respect to the quinone, first order with respect to hydrogen peroxide, and inverse first order with respect to hydrogen ion, which is interpreted by a rate controlling reaction between the quinone and the mononeg. hydroperoxide ion. Activation parameters are reported for each substituted quinone except for the 2-tert-Bu derivative, where the influence of parallel and consecutive processes made it impossible to determine these kinetic parameters with satisfactory precision. The trend of the activation parameters was interpreted by Hammett correlation. In the quantum chem. studies, the M06-L functional along with the 6-311+G(d,p) basis set was used to optimize the relevant structures including the transition states of the rate controlling step. The results of the theor. calculations were in reasonable agreement with the exptl. findings. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Synthetic Route of C9H10O4).
2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Synthetic Route of C9H10O4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem