Aromatic substitution. XXXV. Boron trifluoride catalyzed nitration of benzene, alkylbenzenes, and halobenzenes with methyl nitrate in nitromethane solution was written by Olah, George A.;Lin, Henry C.. And the article was included in Journal of the American Chemical Society in 1974.Recommanded Product: 5367-32-8 This article mentions the following:
The competitive rates and isomer distributions of the BF3-catalyzed nitration of benzene, alkyl-, halo-, and substituted polymethylbenzenes with MeNO3 in MeNO2 were determined Relative nitration rates of alkylbenzenes correlated more closely with the stability of the corresponding π complexes than those of the σ complexes. This trend is greatly enhanced with increasing alkyl substitution. Relative rates of nitration of substituted benzenes, 3-substituted toluenes, 2-substituted p-xylenes, and 3-substituted durenes were correlated with help of the Yukawa-Tsuno equation. The correlation of r values with the nature of the transition states involved is discussed. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Recommanded Product: 5367-32-8).
3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Recommanded Product: 5367-32-8
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem