Microbiological enantioselective synthesis of (S) and (R) 4-(p-anisyloxy)-3-hydroxybutyrates as new chiral building blocks for the synthesis of β-lactam antibiotics was written by Banfi, Luca;Cascio, Giuseppe;Ghiron, Chiara;Guanti, Giuseppe;Manghisi, Elso;Narisano, Enrica;Riva, Renata. And the article was included in Tetrahedron in 1994.Formula: C9H10O4 This article mentions the following:
Both enantiomers of 4-(p-anisyloxy)-3-hydroxybutanoates 4-MeOC6H4OCH2CH(OH)CH2CO2R (R = Et, CH2Ph) have been prepared in high e.e. by reduction of the corresponding β-keto esters or β-keto carboxylates with immobilized fermenting baker’s yeast. The utility of these new chiral building blocks in the synthesis of pharmacol. important β-lactam antibiotics has been demonstrated. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Formula: C9H10O4).
2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Formula: C9H10O4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem