Investigation of the relationship between the inhibitory activity of glycolic acid oxidase (GAO) and its chemical structure: electron-topological approach was written by Guzel, Y.. And the article was included in Journal of Molecular Structure: THEOCHEM in 1996.Synthetic Route of C9H10O4 This article mentions the following:
Rules for the occurrence of the inhibitory activity of glycolic acid oxidase are formulated and discussed in terms of the so-called electron-topol. approach. It is shown that the mol. fragment responsible for this kind of activity possesses fixed electronic and geometrical characteristics caused by a definite spatial arrangement of an oxygen atom and a group of carbon atoms. A series of 85 compounds including 36 active and 49 inactive compounds was studied. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4Synthetic Route of C9H10O4).
2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Synthetic Route of C9H10O4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem