Synthesis of symmetrical secondary oligoethylene glycolated amines from diethanolamine was written by Yang, Hao;Li, Yu;Lin, Ruoyun;Ouyang, Zhen;Han, Mingli;Zhu, Lijun;Chen, Shizhen;Zhou, Xin;Jiang, Zhong-Xing. And the article was included in Organic & Biomolecular Chemistry in 2022.Formula: C5H12O3 This article mentions the following:
Monodisperse oligoethylene glycols (M-OEGs)-containing sym. secondary amines are highly valuable synthetic intermediates in drug development and materials sciences. Scalable three-step synthesis of M-OEGs secondary amines with flexible M-OEGs and/or alkyl chains is described herein. Through reduction amination of diethanolamine, Williamson ether synthesis, and subsequent deprotection, a series of M-OEGs secondary amines with diverse and fine-tunable chem. structures were conveniently prepared The presented strategy is attractive with readily available starting materials, simple catalytic systems, scalable synthesis, and avoids the use of explosive sodium azide. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Formula: C5H12O3).
2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Formula: C5H12O3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem