Switchable ROS Species Regulation Facilitates the Selective Oxidation of Benzyl Alcohols Enabled by an Organic Photocatalyst was written by Jia, Meng-Ze;Cui, Jing-Wang;Rao, Cai-Hui;Chen, Yun-Rui;Yao, Xin-Rong;Zhang, Jie. And the article was included in ACS Sustainable Chemistry & Engineering in 2022.Computed Properties of C8H10O2 This article mentions the following:
Benefiting from the regulation of ROS species through a simple and feasible strategy, an efficient and switchable photocatalytic protocol for the chemoselective synthesis of aldehydes and carboxylic acids via oxidation of primary alcs. under mild conditions was developed. Using the pyridinium derivative as a metal-free organic photocatalyst, a variety of benzyl alcs. can be converted into aldehydes or carboxylic acids under an air atm. at room temperature with high selectivity and yield via simple solvent regulation. A feasible tandem reaction combining the pyridinium-catalyzed alc.-to-aldehyde conversion and catalyst-free photoinduced oxidation of aromatic aldehydes provides a powerful and efficient approach for the one-pot oxidation of benzyl alcs. to carboxylic acids, while a small amount of water can effectively regulate the competition of electron transfer and energy transfer and inhibit the generation of carboxylic acids, facilitating highly efficient and selective oxidation of alcs. to aldehydes. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Computed Properties of C8H10O2).
(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Computed Properties of C8H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem