Zhao, Danyue et al. published their research in Molecular Nutrition & Food Research in 2020 | CAS: 2380-78-1

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol

Influence of Diet-Induced Obesity on the Bioavailability and Metabolism of Raspberry Ketone (4-(4-Hydroxyphenyl)-2-Butanone) in Mice was written by Zhao, Danyue;Yuan, Bo;Kshatriya, Dushyant;Polyak, Andrew;Simon, James E.;Bello, Nicholas T.;Wu, Qingli. And the article was included in Molecular Nutrition & Food Research in 2020.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:

Raspberry ketone (RK) is the primary aroma compound in red raspberries and a dietary supplement for weight loss. This work aims to (1) compare RK bioavailability in male vs. female, normal-weight vs. obese mice; (2) characterize RK metabolic pathways. Study 1: C57BL/6J male and female mice fed a low-fat diet (LFD; 10% fat) receive a single oral gavage dose of RK (200 mg kg-1). Blood, brain, and white adipose tissue (WAT) are collected over 12 h. Study 2: Male mice are fed a LFD or high-fat diet (45% fat) for 8 wk before RK dosing. Samples collected are analyzed by UPLC-MS/MS for RK and its metabolites. RK is rapidly absorbed (Tmax ≈ 15 min), and bioconverted into diverse metabolites in mice. Total bioavailability (AUC0-12h) is slightly lower in females than males (566 vs 675 nmol mL-1 min-1). Total bioavailability in obese mice is almost doubled that of control mice (1197 vs 679 nmol mL-1 min-1), while peaking times and elimination half-lives are delayed. Higher levels of RK and major metabolites are found in WAT of the obese than normal-weight animals. RK is highly bioavailable, rapidly metabolized, and exhibits significantly different pharmacokinetic behaviors between obese and control mice. Lipid-rich tissues, especially WAT, can be a direct target of RK. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Recommanded Product: 4-Hydroxy-3-methoxyphenethanol).

4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 4-Hydroxy-3-methoxyphenethanol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem