Pyrano-[2,3b]-pyridines as potassium channel antagonists was written by Finlay, Heather J.;Lloyd, John;Nyman, Michael;Conder, Mary Lee;West, Tonya;Levesque, Paul;Atwal, Karnail. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2008.Quality Control of N-(3-Methoxybenzyl)ethanamine The following contents are mentioned in the article:
The design and synthesis of a series of highly functionalized pyrano[2,3-b]pyridines is described. These compounds were assayed for their ability to block the IKur channel encoded by the gene hKV1.5 in patch-clamped L-929 cells. Six of the compounds in this series showed sub-micromolar activity, the most potent being 4-(4-ethylbenzenesulfonylamino)-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-6-carboxylic acid N-ethyl-N-phenylamide with an IC50 of 378 nM. This study involved multiple reactions and reactants, such as N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3Quality Control of N-(3-Methoxybenzyl)ethanamine).
N-(3-Methoxybenzyl)ethanamine (cas: 140715-61-3) belongs to ethers. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Quality Control of N-(3-Methoxybenzyl)ethanamine
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem