An improved method for the synthesis of 5-arylidene barbiturates using BiCl3 was written by Khan, Khalid Mohammed;Ali, Muhammad;Farooqui, Tanveer Ahmad;Khan, Momin;Taha, Muhammad;Perveen, Shahnaz. And the article was included in Journal of the Chemical Society of Pakistan in 2009.Application In Synthesis of 3-Hydroxy-5-methoxybenzaldehyde This article mentions the following:
An improved and eco-benign synthesis of arylidene barbiturates has been developed by using bismuth chloride (BiCl3) in water. Execution is simple and products yields were very high. All the reactions were completed in 30 min time. The new methodol. does not involve any solvent/solvent extraction while solid products were obtained in all cases which were filtered and washed. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Application In Synthesis of 3-Hydroxy-5-methoxybenzaldehyde).
3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Application In Synthesis of 3-Hydroxy-5-methoxybenzaldehyde
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem