Arene Ru (II)-catalyzed facile synthesis of N-acylhydrazones via acceptorless dehydrogenative coupling strategy was written by Sundar, Saranya;Rengan, Ramesh;Pennamuthiriyan, Anandaraj;Semeril, David. And the article was included in Applied Organometallic Chemistry in 2022.Formula: C8H10O2 This article mentions the following:
A facile catalytic one-pot synthesis of N-acylhydrazones via acceptorless dehydrogenative coupling of readily available alcs. and benzohydrazides (R2CONHNH2) using arene ruthenium (II) complexes was described. The coupling of alcs. with various benzohydrazides using ruthenium catalysts provide a wide range of N-acylhydrazones in good to excellent yields (63-93%; 32 examples). The present protocol offers high selectivity of hydrazones without any alkylated products and tolerates a range of functional groups. Control experiments indicate that the mechanism proceeds via acceptorless dehydrogenation of alcs., and hydrogen and water are the sole byproducts. The gram scale synthesis illustrates the usefulness of the present strategy. In the experiment, the researchers used many compounds, for example, (4-Methoxyphenyl)methanol (cas: 105-13-5Formula: C8H10O2).
(4-Methoxyphenyl)methanol (cas: 105-13-5) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Formula: C8H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem