Propargylation of CoQ0 through the Redox Chain Reaction was written by Pawlowski, Robert;Stodulski, Maciej;Mlynarski, Jacek. And the article was included in Journal of Organic Chemistry in 2022.HPLC of Formula: 605-94-7 This article mentions the following:
An efficient catalytic propargylation of CoQ0 (2,3-dimethoxy-5-methyl-p-benzoquinone) is described by employing the cooperative effect of Sc(OTf)3 and Hantzsch ester. It is suggested to work through the redox chain reaction, which involves hydroquinone and dimeric propargylic moiety intermediates. A broad range of propargylic alcs. can be converted into the appropriate derivatives of CoQ0 containing triple bonds, I [R1 = Ph, 4-ClC6H4, 3-Cl-4-MeOC6H4, 2-thienyl, etc., R2 = SiMe3, cyclopropyl, 2-naphthyl, etc.], in good to excellent yields. The mechanism of the given transformation is also discussed. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7HPLC of Formula: 605-94-7).
2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.HPLC of Formula: 605-94-7
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem