New access to indoles by ylide-amide condensation was written by Le Corre, M.;Hercouet, A.;Le Stanc, Y.;Le Baron, H.. And the article was included in Tetrahedron in 1985.Related Products of 5367-32-8 This article mentions the following:
o-Acylaminobenzylidenephosphoranes lead to indoles in good yield by an intramol. Wittig reaction with the amide carbonyl group. Mechanistic aspects are discussed. A general method is described for the synthesis of indoles from o-nitrobenzyl bromides and o-aminobenzyl alcs. Thus, o-AcNHC6H4CH2PPh3, prepared in 3 steps from 2-O2NC6H4Me, was treated with base to give the indole I in 96% yield. In the experiment, the researchers used many compounds, for example, 3-Methyl-4-nitroanisole (cas: 5367-32-8Related Products of 5367-32-8).
3-Methyl-4-nitroanisole (cas: 5367-32-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Related Products of 5367-32-8
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem