Kinetic studies of the transesterification of dimethyl phosphite by alcohols of the guaiacyl and veratryl series was written by Vasil’eva, V. P.;Lykhina, G. G.. And the article was included in Izvestiya Tomskogo Politekhnicheskogo Instituta in 1976.Category: ethers-buliding-blocks This article mentions the following:
The reactivity of alcs. in the title reaction decreased in the order 1-guaiacyl-1-propanol > 1-veratryl-1-propanol (I) > 1-guaiacyl-3-propanol > PhCHEtOH > 1-veratryl-3-propanol (II); the rate constant for I was 15 times that for II. The absence of substituents on the Ph ring deactivated the OH group in the α-position of the propanol side chain. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3Category: ethers-buliding-blocks).
3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Electron-deficient reagents are also stabilized by ethers. For example, borane (BH3) is a useful reagent for making alcohols. Pure borane exists as its dimer, diborane (B2H6), a toxic gas that is inconvenient and hazardous to use. Borane forms stable complexes with ethers, however, and it is often supplied and used as its liquid complex with tetrahydrofuran (THF).Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem