461-82-5, The chemical industry reduces the impact on the environment during synthesis 461-82-5, name is 4-(Trifluoromethoxy)aniline, I believe this compound will play a more active role in future production and life.
A method for preparing 2,6-dibromo-4- (trifluoromethoxy) aniline,Including the following steps:The sodium sulfate was filtered off embodiment Example 4 156g crystallization mother liquor into 250mL 4-neck flask,Start stirring dropping 17.5 (0.175mol) sulfuric acid,Then, 36.5 g of sodium bromide (0.354 moL) was added and then 30 g (99percent, 0.168 mol) of 4-trifluoromethoxyaniline was added.Adjust the temperature to above 30 ,Start dropping 35percent hydrogen peroxide 38g,When dropping temperature rise,When the temperature rose to 50 ,By controlling the cooling liquid dripping temperature control between 50 ~ 55 ,Keep the temperature drops off,Drip finished insulation 3 hours,Cooling to about 30 ,filter,Filter cake drying,White crystals of 2,6-dibromo-4-trifluoromethoxyaniline 55.8 g, purity99.6percent (HPLC), yield 99.2percent.
The chemical industry reduces the impact on the environment during synthesis 4-(Trifluoromethoxy)aniline. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Yancheng Limin Agrochemical Co., Ltd.; Huang Haijun; Zhu Mingliang; (7 pag.)CN106631839; (2017); A;,
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