Adding a certain compound to certain chemical reactions, such as: 4179-19-5, name is 3,5-Dimethoxytoluene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 4179-19-5, 4179-19-5
1,3-Dimethoxy-5-methylbenzene (30 g, 0.20 mol)And dichloromethane (900 mL) was added to a dry round bottom flask (1 L).Cooling to the above solution in an ice bath sulfuryl chloride (52.5 g, 0.40 mol) was added dropwise.After the dropwise addition was completed, the mixture was stirred at room temperature overnight. After the reaction,Add sodium bicarbonate aqueous sodium hydrogencarbonate solution to adjust pH=8, extract with dichloromethane,Washed with dilute hydrochloric acid, distilled water, and dried,Concentration under reduced pressure gave the compound 2,4-dichloro-1,5-dimethoxy-3-methylbenzene (31 g, white solid).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,5-Dimethoxytoluene, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Rudong Lingda Bio-pharmaceutical Technology Co., Ltd.; Wang Hui; (76 pag.)CN109721600; (2019); A;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem