A common heterocyclic compound, 43229-65-8, name is N-Benzyl-1-(4-methoxyphenyl)propan-2-amine, molecular formula is C17H21NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 43229-65-8.
Synthesis of 4-benzyloxy-3-methoxymethyl-alpha[N-benzyl-N(alpha-methyl-4-methoxyphenethyl)amino]acetophenone Amounts of 39.5 g of the compound obtained in the step C1 and 57.7 g of N-benzyl-N(alpha-methyl-4-methoxyphenethyl)amine are stirred for 6 hours in 200 ml of acetonitrile. The crystals precipitated are filtered off, and the filtrate is concentrated, to give the object compound. The compound is used for the following step without purification.
The synthetic route of N-Benzyl-1-(4-methoxyphenyl)propan-2-amine has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Eisai Co., Ltd.; US4317930; (1982); A;,
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