As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 2752-17-2 name is 2,2′-Oxydiethanamine, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. 2752-17-2
For the synthesis of H2L, salicylic aldehyde (10 mmol, 1.22 g) in EtOH(5 mL) was added dropwise into a 5-mL EtOH solution of 3-oxapentane-1,5-diamine (5 mmol,0.52 g). Then, the solution was stirred for 4 h at 78 C. After cooling to room temperature, the precipitate was filtered. The product was dried in vacuo, and a yellow crystalline solid obtained. Yield: 1.19 g (68.5 %). Calcd. (%) forC18H20O3N2: C, 69.21; H, 6.45; N, 8.97. Found (%): C, 69.09; H, 6.54; N, 8.83.1H NMR (CDCl3 400 MHz) d/ppm: 8.30 (s, 2H, N=C-H), 6.79-7.33 (m, 8H,H-benzene ring), 3.66-3.74 (m, 8H, O-(CH2)2-N=C). UV-Vis (k, nm): 268, 316.FT-IR (KBr m/cm-1): 1,637, m(C=N); 1,286, m(C-O-C); 3,458, m(OH) stretching frequency, respectively.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 2,2′-Oxydiethanamine, and friends who are interested can also refer to it.
Reference:
Article; Wu, Huilu; Pan, Guolong; Bai, Yuchen; Wang, Hua; Kong, Jin; Shi, Furong; Zhang, Yanhui; Wang, Xiaoli; Research on Chemical Intermediates; vol. 41; 6; (2015); p. 3375 – 3388;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem