Related Products of 4344-55-2,Some common heterocyclic compound, 4344-55-2, name is 4-Butoxyaniline, molecular formula is C10H15NO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: Compound 51 (1.00 mmol) was suspended in dry acetonitrile (10 mL) under nitrogen atmosphere. Relevant aniline (1.00 mmol) and 4-dimethylaminopyridine (4.00 mmol) were successively added dropwise and the mixture was stirred at room temperature for 48 h. Ethyl acetate was added and the solution was washed with hydrochloric acid 1N, brine, dried over sodium sulfate, filtered, and evaporated to dryness under vacuum. The white solid was purified by flash chromatography on silica gel.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 4-Butoxyaniline, its application will become more common.
Reference:
Article; Fortin, Sebastien; Wei, Lianhu; Moreau, Emmanuel; Lacroix, Jacques; Cote, Marie-France; Petitclerc, Eric; Kotra, Lakshmi P.; Gaudreault, Rene C.; European Journal of Medicinal Chemistry; vol. 46; 11; (2011); p. 5327 – 5342;,
Ether – Wikipedia,
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