Adding a certain compound to certain chemical reactions, such as: 107622-80-0, name is (4-Phenoxyphenyl)methanamine, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 107622-80-0, Computed Properties of C13H13NO
A mixture of ethyl 5-(3,5-dichloro-4-hydroxyphenyl)-1,3,4-oxadiazole-2-carboxylate (0.3003 g, 0.990 mmol) and 4-phenoxybenzylamine (0.5922 g, 2.97 mmol) in ethanol (10 mL) was stirred at 80 C. under nitrogen for 2 d. The mixture was partitioned between dilute aqueous HCl (50 mL) and ethyl acetate (75 mL). The aqueous layer was extracted further with ethyl acetate (50 mL) and the combined extracts were washed with brine (30 mL), dried (MgSO4) and evaporated. The residue was purified by flash chromatography (silica gel, 2% MeOH/CH2Cl2) to give 0.4235 g (94%) of the title compound as a white solid.
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Reference:
Patent; Institute for OneWorld Health; US2010/267725; (2010); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem