Adding a certain compound to certain chemical reactions, such as: 768-70-7, name is 3-Ethynylanisole, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 768-70-7, category: ethers-buliding-blocks
General procedure: To the mixture of terminal alkyne (1mmol), water (2.0 equiv), and acetic acid (2 mL), silver tetrafluoroborate (5 mol%) was added. The mixture was stirred at 110C for 10 h. Water (10 mL) was added and the solution was extracted with ethyl acetate (3¡Á8 mL), the combined extract was dried with anhydrous MgSO4. The solvent was removed and the crude product was separated by column chromatography to give the pure sample. 4.2.8. 1-(3-Methoxyphenyl)ethanone (2h). 1H NMR (400 MHz, CDCl3): delta=7.41-7.47 (m, 2H), 7.26-7.31 (m, 1H), 7.02-7.04 (m, 1H), 3.77 (s, 3H), 2.51 (s, 3H). 13C NMR (100 MHz, CDCl3): delta=197.7, 159.7, 138.4, 129.5, 121.0, 119.4, 112.3, 55.3, 26.6. MS (EI) m/z: 150, 135, 107, 92, 77, 63.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3-Ethynylanisole, and friends who are interested can also refer to it.
Reference:
Article; Chen, Zheng-Wang; Ye, Dong-Nai; Qian, Yi-Ping; Ye, Min; Liu, Liang-Xian; Tetrahedron; vol. 69; 30; (2013); p. 6116 – 6120;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem