Synthetic Route of 702-24-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 702-24-9 name is 4-Methoxy-N-methylbenzylamine, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
General procedure: A secondary amine (0.34 mol), sodium methoxide (0.35 mol), diethyl ether (600 mL), and methanol (90 mL) were placed into a 1 L three-neck flask equipped with a stirrer, a condenser with a liquid valve, and a gas inlet. A flow of NO was passed at ~20 ¡ãC with vigorous stirring for 10 ?12 h at a rate allowing to maintainan excessive gas pressure within 13 ? 20 Torr. A dense precipitate formed was filtered, washed with diethyl ether, dried first on the filter, then in vacuo using an oil pump to obtain the corresponding sodium salts.
At the same time, in my other blogs, there are other synthetic methods of this type of compound, 4-Methoxy-N-methylbenzylamine, and friends who are interested can also refer to it.
Reference:
Article; Smirnov; Gordeev; Nikitin; Pokhvisneva; Ternikova; Luk?yanov; Russian Chemical Bulletin; vol. 64; 11; (2015); p. 2712 – 2717; Izv. Akad. Nauk, Ser. Khim.; 11; (2015); p. 2712 – 2717,6;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem