Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 538-86-3, name is (Methoxymethyl)benzene, A new synthetic method of this compound is introduced below., Recommanded Product: (Methoxymethyl)benzene
General procedure: TsNBr2 (98.7 mg, 0.30 mmol) was added in one portion to a stirred solution of ether (0.20 mmol) andK2CO3 (137.9 mg, 1.0 mmol) in DCM (2.0 mL). The mixture was stirred at 40 ¡ãC for 4 h, and thereaction mixture was cooled to room temperature. Then the reaction was quenched with sat. aqNa2SO3 (2.0 mL) and water (2.0 mL). The mixture was extracted with DCM (3 ¡Á 5.0 mL) and theextracts were combined, washed with brine (10.0 mL), dried over Na2SO4, filtered, and concentratedin vacuo. The residue was purified by flash column chromatography (silica gel, PE-EtOAc) to givethe corresponding product
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Wang, Yuan-Yuan; Sun, Ming-Hui; Zeng, Ning-Ning; Chen, Jie; Zhou, Ling; Synlett; vol. 27; 9; (2016); p. 1438 – 1442;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem