Some common heterocyclic compound, 702-24-9, name is 4-Methoxy-N-methylbenzylamine, molecular formula is C9H13NO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C9H13NO
Respectively, weighed o-iodobenzoic acid 252 mg,N-methyl-4-methoxybenzylamine 68 mg was added to 10 ml of chloroform,The reaction was stirred under reflux for 6 hours.Natural cooling to room temperature after pumping to remove IBX And its reduction products o-iodo benzoic acid(IBA),The filtrate was washed with 10percent Na0H solution,1M hydrochloric acid, water and saturated sodium chloride solution were washed 3 times,Each about 10 ml,The solvent chloroform was removed by rotary evaporation,The product was directly characterized by NMR, and the yield of 4-methoxybenzaldehyde was 91percent.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 702-24-9, its application will become more common.
Reference:
Patent; Guizhou University; CONG, Hang; WANG, Fang; TAO, Zhu; (8 pag.)CN105732351; (2016); A;,
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