Related Products of 21388-17-0,Some common heterocyclic compound, 21388-17-0, name is 2-Ethyl-6-methoxynaphthalene, molecular formula is C13H14O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 9 Preparation of 2-Methoxy-6-(1-Bromoethyl) Naphthalene: A mixture of 1.0 gram of 2-methoxy-6-ethylnaphthalene and 1.05 grams of N-bromosuccinimide in 10.0 ml. of carbon tetrachloride was refluxed for 1 hour. During this time, the solids migrated from the bottom of the reaction flask to the top. The mixture was cooled to room temperature and the solids were separated from the liquid by filtration on a small suction filter funnel. The carbon tetrachloride solvent was removed using a rotary vacuum evaporator. The yield was 1.55 grams of a pale oil that solidified at room temperature. Based on 1 H nuclear magnetic resonance data, the product had a structure consistent with that of 2-methoxy-6- (1-bromoethyl) naphthalene.
The synthetic route of 21388-17-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Amoco Corporation; US5235115; (1993); A;,
Ether – Wikipedia,
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