A new synthetic route of 592-55-2

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromo-2-ethoxyethane, other downstream synthetic routes, hurry up and to see.

Related Products of 592-55-2, The chemical industry reduces the impact on the environment during synthesis 592-55-2, name is 1-Bromo-2-ethoxyethane, I believe this compound will play a more active role in future production and life.

Potassium carbonate (2.43 g, 17.56 mmol) and ethyl bromoacetate (1.76 g, 10.54 mmol) were added to a solution of bis (2- (1- methylimidazolyl) methyl) amine(Lll) (1.8 g, 8.78 mmol) in dimethylfonnamide under an argon atmosphere. The resulting suspension was sheltered from light and allowed to stir at room temperature for 5 days. Water was added to the resulting mixture, and the solution was extracted with chloroform (3 x 50 mL). After the solvent was evaporated, the resulting oil was purified by silica gel column chromatography using a MeOH/CHC13 (5: 95) solution to giveLllEt as white powder. Yield: 1.05 g (41%). 1H NMR((ppm), MeOH-d4) : 6.87 (d, J) 1.2 Hz, 2H, ImH), 6.79(d, J) 1.2 Hz, 2H, ImH), 4.06 (q, J) 14.4 Hz, 2H,OCH2), 3.75 (s, 4H, ImCH2), 3.51 (s, 6H,NCH3), 3.35 (s, 2H, NCH2CO2), 1.19 (t, J) 7.2 Hz, 3H,CHs).”C NMR(b(ppm), MeOH-d4) : 172.09 (C,C02Et), 146.24 (2C, Im), 127.17 (2CH, Im), 123.79 (2CH, Im), 61.73 (C, OCH2), 55.03 (2C, ImCH2), 52.37 (2C,NCH3), 33.24 (C,NCH2), 14.67 (C, CH3).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Bromo-2-ethoxyethane, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; MOLECULAR INSIGHT PHARMACEUTICALS; WO2005/79865; (2005); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem