Analyzing the synthesis route of 6876-00-2

The chemical industry reduces the impact on the environment during synthesis 1-Bromo-3-phenoxybenzene. I believe this compound will play a more active role in future production and life.

Application of 6876-00-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6876-00-2, name is 1-Bromo-3-phenoxybenzene, This compound has unique chemical properties. The synthetic route is as follows.

EXAMPLE 18 4-(4-Chlorophenyl)-2-fluoro-4-methyl-1-(3-phenoxyphenyl)pent-2-ene The method of Example 16 was repeated using a Grignard reagent, prepared from 3-phenoxyphenyl bromide (0.19 g), tetrahydrofuran (2 ml) and magnesium (22 g), and 4-(4-chlorophenyl)-2-fluoro-4-methylpent-2-enyl acetate (Example 13) (0.12 g). The residue after evaporation was purified by preparative thin layer chromatography (solvent: diethyl ether/hexane; 1:9) and then preparative high performance liquid chromatography (column: C18; solvent: methanol; flow rate: 3 ml/min; to give the title compound (38 mg, 22%).

The chemical industry reduces the impact on the environment during synthesis 1-Bromo-3-phenoxybenzene. I believe this compound will play a more active role in future production and life.

Reference:
Patent; British Technology Group, Ltd.; US5880162; (1999); A;,
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