Reference of 7664-66-6,Some common heterocyclic compound, 7664-66-6, name is 4-Isopropoxyaniline, molecular formula is C9H13NO, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
The compound obtained in Reference Example 1-2 (19mg) and 4-isopropoxyaniline (10mg) was dissolved in acetonitrile (1.5 mL). And reacted for 10 minutes at the microwave irradiation under 180 C. After the solvent was concentrated to give the title compound purified by silica gel column chromatography (17mg, 60%).
The synthetic route of 7664-66-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; TAIHO PHARMACEUTICAL COMPANY LIMITED; MINAMIGUCHI, KAZUHISA; OKAJIMA, SHIGEO; AOKI, SHINICHI; ASAI, MASANORI; ASAI, TAKAHIRO; YAMANAKA, HIROYOSHI; DOHI, SUGURU; (149 pag.)JP5851663; (2016); B1;,
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