In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1462-37-9, name is ((2-Bromoethoxy)methyl)benzene belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Safety of ((2-Bromoethoxy)methyl)benzene
0.24 g (10 mmo 1) sodium hydride and 15 ml of N, N-dimethylformamide were added to a 50 ml round bottom flask,Stirred at room temperature for 10 minutes,Followed by the addition of 2.5 g (lOmmol) of compound 2 and 1 O of 2-octyloxyethyl bromide,And the reaction was carried out by thin layer chromatography to the end of the reaction. The reaction solution was then poured into 500 ml of ice water and extracted three times with 100 ml of ethyl acetate. The organic phase was combined and the solvent was evaporated. The residue was purified by WATFif = 100: 1 ) To give Compound 3 (2.7 g, 71% yield)
The synthetic route of 1462-37-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guangxi Normal University; Chen Zhenfeng; Liang Hong; Liu Yancheng; Li Liangping; Lu Xing; (13 pag.)CN106478675; (2017); A;,
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