Reference of 4342-46-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4342-46-5, name is 4-Methoxycyclohexanamine, This compound has unique chemical properties. The synthetic route is as follows.
High pressure reactor1200 mL of water was added thereto, stirring was started, 220 g (2 mol) of formamide having a concentration of 40% was added, and after stirring for 10 minutes, 130 g (1 mol) of 1-amino-4-methoxycyclohexane was added, and 7 g of a ruthenium carbon catalyst was further added. Passing CO into the reactor,Pressure in the kettleThe force reaches 0.2MPa, the temperature is raised to 50 C, the temperature is kept for 20h, and the medium-controlled raw material is <2%.After the reaction is completed, the temperature is lowered to 25 to 30 C, dilute hydrochloric acid is added dropwise to the reaction solution, the pH is adjusted to 5 to 6, a solid is precipitated, the product is filtered off, and the filter cake is washed once to obtain cis-8-methoxy-1. 3-Diazaspiro [4,5]-indol-2,4-dione 169g, yield 84.5%;
The chemical industry reduces the impact on the environment during synthesis 4-Methoxycyclohexanamine. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Henan Longhu Biological Co., Ltd.; Wang Huiqin; Li Shouhu; Guo Shuai; Mao Longfei; (14 pag.)CN107827883; (2018); A;,
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