Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 1836-62-0, Name is 2-(2-Methoxyphenoxy)ethylamine, SMILES is COC1=CC=CC=C1OCCN, belongs to ethers-buliding-blocks compound. In a document, author is Li, Cong, introduce the new discover, Application In Synthesis of 2-(2-Methoxyphenoxy)ethylamine.
A fluorescence strategy for monitoring alpha-glucosidase activity and screening its inhibitors from Chinese herbal medicines based on Cu nanoclusters with aggregation-induced emission
Herein, the self-assembly of 1-dodecanethiol-capped Cu nanoclusters (DT-Cu NCs) is obtained by annealing of dibenzyl ether solution of nanoclusters. These aggregates are composed of small clusters and emit a high level of aggregation-induced emission (AIE) in water. Based on the quenching effect of 4-nitrophenol (4-NP) on DT-Cu NCs, a fluorescence strategy is developed to monitor alpha-glucosidase (alpha-Glu) activity and screen its inhibitors from Chinese herbal medicines. 4-Nitrophenyl-alpha-D-glucopyranoside (NGP) is selected as the substrate, which is further hydrolyzed to yield 4-NP through the catalysis of alpha-Glu. The quenching efficiency is positively correlated to the concentration of alpha-Glu. Furthermore, the inhibitory effects of the extracts from four Chinese herbal medicines (i.e., the rind of Punica granatum L., Momordica grosvenorii Swingle., Crataegus pinnatifida Bge., and Lycium barbarum L.) on the alpha-Glu activity have been studied. The IC50 values of extracts from the rind of Punica granatum L. and Momordica grosvenorii Swingle are 0.23 and 0.37 g/L, respectively, so they show obvious inhibitory effects on alpha-Glu. The extracts of Crataegus pinnatifida Bge. and Lycium barbarum L. exhibit relatively weak inhibitory effects. Hence, the proposed strategy can be applicable for screening alpha-Glu inhibitors from Chinese herbal medicines. Last but not the least, by immobilizing DT-Cu NCs into agarose hydrogels in polyethylene tubes, a visual device is fabricated to screen alpha-Glu inhibitors with high throughput and sensitivity.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 1836-62-0 is helpful to your research. Application In Synthesis of 2-(2-Methoxyphenoxy)ethylamine.