Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 126-38-5, name is 1-Bromo-2,2-dimethoxypropane, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C5H11BrO2
A suspension of 5-bromo-4-fluoropyridin-2-amine (1 g, 5.24 mmol) inisopropanol (10 mL) was treated with 1-bromo-2,2-dimethoxypropane (1.16 g, 6.28mmol). The resulting mixture was heated at 80C for 21 h, then cooled to room temperature and concentrated under vacuum at 40C. The residue was treated with ethyl acetate (15 mL) and water (15 mL) and the phases were separated. The aqueous phase was basified with aqueous NaOH solution (32% w/w) to pH 8, then extracted with ethylacetate (10 mL, then 15 mL). The organic phases were pooled and concentrated under vaccuum at 40C to give the title compound (0.93 g, 78%) as a beige solid.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 126-38-5.
Reference:
Patent; UCB BIOPHARMA SPRL; ALEXANDER, Rikki Peter; BENTLEY, Jonathan Mark; BRACE, Gareth Neil; BROOKINGS, Daniel Christopher; CHOVATIA, Praful Tulshi; DEBOVES, Herve Jean Claude; JOHNSTONE, Craig; JONES, Elizabeth Pearl; KROEPLIEN, Boris; LECOMTE, Fabien Claude; MADDEN, James; MILLER, Craig Adrian; PORTER, John Robert; SELBY, Matthew Duncan; SHAW, Michael Alan; VAIDYA, Darshan Gunvant; YULE, Ian Andrew; WO2015/86506; (2015); A1;,
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem