Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 4179-19-5, name is 3,5-Dimethoxytoluene, A new synthetic method of this compound is introduced below., name: 3,5-Dimethoxytoluene
General procedure: A 25mL round-bottom flask equipped with a magnetic barand a water condenser was charged with propargylic alcohol1 (1.0mmol), arene 2 (1.1mmol), MeCN (2.0mL) andPTSA (10mol%) in air atmosphere. The flask was placedinto a constant temperature oil-bath at 80C and the progressof the reaction was monitored by TLC. After completionof the reaction, the solvent was removed under reducedpressure and the crude reaction mixture was purified by columnchromatography.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.