4463-59-6, name is 1-(2-Bromoethoxy)-2-methoxybenzene, belongs to ethers-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Computed Properties of C9H11BrO2
EXAMPLE 68 4-Benzyl-1-[2-(2-methoxyphenoxy)ethyl]piperidine STR105 From 1-(2-Bromoethoxy)-2-methoxybenzene (515 mg, 2.23 mmol) and 4-benzylpiperidine (785 mg, 4.48 mmol) there was obtained 560 mg (85%) of the amine as a yellowish oil. 1 H NMR (CDCl3): 1.27-1.40 (m, 2H), 1.47-1.58 (m, 1H), 1.62-1.66 (m,2H), 1.99-2.06 (m, 2H), 2.543 (d, 2H, J=7), 2.745 (t, 2H, J=6), 2.95-2.99 (m, 2H), 3.760 (s, 3H), 4.041 (t, 2H, J=6), 6.79-6.85 (m, 4H), 7.13-7.30 (m, 5H). The hydrochloride, mp 165-6 C.
The synthetic route of 4463-59-6 has been constantly updated, and we look forward to future research findings.