Adding a certain compound to certain chemical reactions, such as: 944317-92-4, name is 1-Bromo-4-fluoro-5-isopropyl-2-methoxybenzene, belongs to ethers-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 944317-92-4, SDS of cas: 944317-92-4
lOg (0.0405 mol) product 4, 11.05g(0.04455 mol) 2-methoxycarbonyl-4- trifiuromethylphenylboronic acid, 2.45g tetra-(triphenylphosphine) palladium, 16g anhydrous potassium carbonate and 100 ml tetrahydrofuran were added into a 250 mL 3-neck fiaskto form a suspension. The mixture was heated to reflux overnight, then cooled to room temperature, filtered, poured into 300 mL water, and was extracted by 3><300 mL ethyl acetate. The organic phase was washed by saturated NaCl solution, dried by anhydrous Na2S04 and distilled under vacuum to obtain a yellow solid. Recrystallization in ethyl acetate gave 7.82g of product 5. If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.