Related Products of 24988-36-1, The chemical industry reduces the impact on the environment during synthesis 24988-36-1, name is 1,5-Dibromo-2,4-dimethoxybenzene, I believe this compound will play a more active role in future production and life.
25 parts of the compound represented by the formula (1-52) is converted into tetrahydrofuran.(Kanto Chemical Co., Ltd.)It was dissolved in 111 parts, cooled to -78 C., and while stirring, 234.2 parts of a 2.5 M hexane solution of n-butyllithium (manufactured by Aldrich Co.) was added dropwise.After input,Stir for 45 minutes at -78 C,With cooling to -78 C., 156 parts of iodomethane (manufactured by Tokyo Chemical Industry Co., Ltd.) was added dropwise.After input,It heated up to 23 degreeC and stirred for 5 hours.After the reaction,The reaction mixture was gradually added to 500 parts of ice water.After that, extract with water-toluene solvent,After concentration, 21 parts of crude product was obtained.This crude product is separated and purified by silica gel column chromatography,17 parts of the compound represented by the formula (1-53) were obtained.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,5-Dibromo-2,4-dimethoxybenzene, other downstream synthetic routes, hurry up and to see.