Synthetic Route of 145903-31-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 145903-31-7, name is 7-Methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine belongs to ethers-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Synthesis of S13 and S14 (Scheme 5): To S26 (20 mg, 0.1 mmol) in CH2Cl2 (5 ml) is added triethylamine (30 mg, 0.3 mmol) and phenyl methoxyphosphonyl chloride (38 mg, 0.2 mmol) at 0 C. After stirring for 2 hours at room temperature, the reaction mixture is washed with saturated sodium bicarbonate. Isomers are separated and purified by silica gel column to yield S13 (14 mg, yield: 40%) and S14 (16 mg, yield: 45%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 7-Methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]thiazepine, other downstream synthetic routes, hurry up and to see.