Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 41365-75-7, name is 1-Amino-3,3-diethoxypropane, A new synthetic method of this compound is introduced below., Product Details of 41365-75-7
f) Preparation of intermediate (10)H To a stirred solution of intermediate (9) (287 mmol) in CHC13 (2000 ml) was added 3,3-diethoxy-l-propanamine (474 mmol) at 0C in portions. After the addition, the reaction mixture was stirred at 0C for 1 hour and then at 15C for 2 hours. Thin Layer Chromatography (petroleum ether/ethyl acetate= 5/1) showed that the reaction was completed. The reaction mixture was washed by saturated Na2S03 aqueous (four times with 600 ml) and then saturated NaHC03 aqueous was added until pH = 7. The aqueous layer was extracted by CH2C12 (500 ml). The combined organic phases were washed with brine (800 ml), dried over Na2S04 and concentrated to give the crude product. The crude product was washed by tert-butyl methylether (three times 500 ml) to give 87 g of intermediate (10) (mp. 100.8 – 103.8C).
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.